STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFAIP3TNF alpha induced protein 3. (790 aa)    
Predicted Functional Partners:
RIPK3
Receptor interacting serine/threonine kinase 3.
   
 0.993
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.992
TAX1BP1
Tax1 binding protein 1.
    
 0.985
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.984
TNIP1
TNFAIP3 interacting protein 1.
   
 0.980
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.968
ENSMLEP00000034242
Uncharacterized protein.
   
  0.936
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.924
TRAF1
TNF receptor-associated factor.
   
 0.906
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.905
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.