STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS1DIRAS family GTPase 1. (198 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.920
ITSN2
Intersectin 2.
    
 0.908
ITSN1
Intersectin 1.
    
 0.829
NOS1AP
Nitric oxide synthase 1 adaptor protein.
    
 0.758
LOC105548340
Uncharacterized protein.
   
 0.754
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.716
SCIMP
SLP adaptor and CSK interacting membrane protein.
   
    0.711
SHANK1
SH3 and multiple ankyrin repeat domains 1.
   
 0.698
ENSMLEP00000018349
Uncharacterized protein.
    
 0.684
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.611
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.