node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCY5 | ENSMLEP00000007417 | ENSMLEP00000025078 | ENSMLEP00000007417 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.910 |
ADCY5 | GNAI2 | ENSMLEP00000025078 | ENSMLEP00000005997 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | G protein subunit alpha i2. | 0.905 |
ADCY5 | GNAO1 | ENSMLEP00000025078 | ENSMLEP00000028764 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | G protein subunit alpha o1. | 0.923 |
ADCY5 | GNAS | ENSMLEP00000025078 | ENSMLEP00000004090 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAS complex locus. | 0.966 |
ADCY5 | GNB1 | ENSMLEP00000025078 | ENSMLEP00000020121 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | G protein subunit beta 1. | 0.897 |
ADCY5 | GNB3 | ENSMLEP00000025078 | ENSMLEP00000006092 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | G protein subunit beta 3. | 0.897 |
ADCY5 | GNB4 | ENSMLEP00000025078 | ENSMLEP00000003157 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | G protein subunit beta 4. | 0.897 |
CCR5 | CXCR4 | ENSMLEP00000006376 | ENSMLEP00000003520 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. | 0.954 |
CCR5 | ENSMLEP00000007417 | ENSMLEP00000006376 | ENSMLEP00000007417 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.914 |
CCR5 | GNAI2 | ENSMLEP00000006376 | ENSMLEP00000005997 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | G protein subunit alpha i2. | 0.935 |
CCR5 | GNAO1 | ENSMLEP00000006376 | ENSMLEP00000028764 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | G protein subunit alpha o1. | 0.903 |
CCR5 | GNB1 | ENSMLEP00000006376 | ENSMLEP00000020121 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | G protein subunit beta 1. | 0.955 |
CCR5 | GNB3 | ENSMLEP00000006376 | ENSMLEP00000006092 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | G protein subunit beta 3. | 0.906 |
CCR5 | GNB4 | ENSMLEP00000006376 | ENSMLEP00000003157 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | G protein subunit beta 4. | 0.955 |
CHRM2 | ENSMLEP00000007417 | ENSMLEP00000001233 | ENSMLEP00000007417 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.913 |
CHRM2 | GNAI2 | ENSMLEP00000001233 | ENSMLEP00000005997 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha i2. | 0.898 |
CHRM2 | GNAO1 | ENSMLEP00000001233 | ENSMLEP00000028764 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha o1. | 0.890 |
CHRM2 | GNB1 | ENSMLEP00000001233 | ENSMLEP00000020121 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit beta 1. | 0.915 |
CHRM2 | GNB3 | ENSMLEP00000001233 | ENSMLEP00000006092 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit beta 3. | 0.903 |
CHRM2 | GNB4 | ENSMLEP00000001233 | ENSMLEP00000003157 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit beta 4. | 0.951 |