STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINA3Serpin family A member 3; Belongs to the serpin family. (423 aa)    
Predicted Functional Partners:
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.889
PROC
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.628
EDN3
Endothelin 3.
     
 0.589
CTSG
Cathepsin G; Belongs to the peptidase S1 family.
    
 0.559
ORM1
Alpha-1-acid glycoprotein; Functions as transport protein in the blood stream. Belongs to the calycin superfamily. Lipocalin family.
   
 0.555
CA6
Carbonic anhydrase 6; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.554
KLK2
Kallikrein related peptidase 2; Belongs to the peptidase S1 family.
    
 0.539
LRP2
LDL receptor related protein 2.
    
 0.532
ALB
Albumin.
   
 0.521
BPIFA1
BPI fold containing family A member 1.
     
 0.513
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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