STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGI4Leucine rich repeat LGI family member 4. (537 aa)    
Predicted Functional Partners:
ADAM22
ADAM metallopeptidase domain 22.
     
 0.761
ADAM11
ADAM metallopeptidase domain 11.
     
 0.684
GJC3
Gap junction protein gamma 3; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family.
      
 0.590
RIMS1
Regulating synaptic membrane exocytosis 1.
      
 0.537
CACNA1A
Calcium voltage-gated channel subunit alpha1 A.
   
  
 0.533
ZDBF2
Zinc finger DBF-type containing 2.
     
 0.531
ADAM23
ADAM metallopeptidase domain 23.
     
 0.531
PPP1R9A
Protein phosphatase 1 regulatory subunit 9A.
      
 0.525
PPP3CA
Serine/threonine-protein phosphatase.
      
 0.485
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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