MTHFR protein (Mandrillus leucophaeus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

MTHFR

Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (697 aa)

Predicted Functional Partners:

CTH

0.988

MTR

0.987

SHMT2

0.962

BHMT

0.956

BHMT2

0.956

TYMS

0.948

AMT

0.947

MAT2A

0.946

MAT1A

0.946

SHMT1

0.946

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMT	BHMT	ENSMLEP00000021692	ENSMLEP00000011408	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	0.664
AMT	BHMT2	ENSMLEP00000021692	ENSMLEP00000026469	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	0.664
AMT	CTH	ENSMLEP00000021692	ENSMLEP00000021928	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Cystathionine gamma-lyase.	0.404
AMT	MAT1A	ENSMLEP00000021692	ENSMLEP00000009636	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.465
AMT	MAT2A	ENSMLEP00000021692	ENSMLEP00000009409	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.465
AMT	MTHFR	ENSMLEP00000021692	ENSMLEP00000008318	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.947
AMT	MTR	ENSMLEP00000021692	ENSMLEP00000031901	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.925
AMT	SHMT1	ENSMLEP00000021692	ENSMLEP00000025931	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.966
AMT	SHMT2	ENSMLEP00000021692	ENSMLEP00000015335	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.965
AMT	TYMS	ENSMLEP00000021692	ENSMLEP00000017773	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Thymidylate synthetase.	0.931
BHMT	AMT	ENSMLEP00000011408	ENSMLEP00000021692	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.664
BHMT	CTH	ENSMLEP00000011408	ENSMLEP00000021928	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Cystathionine gamma-lyase.	0.930
BHMT	MAT1A	ENSMLEP00000011408	ENSMLEP00000009636	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.904
BHMT	MAT2A	ENSMLEP00000011408	ENSMLEP00000009409	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.900
BHMT	MTHFR	ENSMLEP00000011408	ENSMLEP00000008318	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.956
BHMT	MTR	ENSMLEP00000011408	ENSMLEP00000031901	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.899
BHMT	SHMT1	ENSMLEP00000011408	ENSMLEP00000025931	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.641
BHMT	SHMT2	ENSMLEP00000011408	ENSMLEP00000015335	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.641
BHMT	TYMS	ENSMLEP00000011408	ENSMLEP00000017773	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Thymidylate synthetase.	0.693
BHMT2	AMT	ENSMLEP00000026469	ENSMLEP00000021692	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.664