STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY3Sprouty RTK signaling antagonist 3. (288 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.838
CBLB
Cbl proto-oncogene B.
    
 0.838
RENBP
Renin binding protein.
      
 0.700
TGIF2LY
TGFB induced factor homeobox 2 like Y-linked.
      
 0.595
SEMA4F
Ssemaphorin 4F; Belongs to the semaphorin family.
      
 0.538
GRAP
GRB2 related adaptor protein.
    
 0.520
GRB2
Growth factor receptor bound protein 2.
    
 0.520
GRAP2
GRB2 related adaptor protein 2.
    
 0.520
HBEGF
Heparin binding EGF like growth factor.
   
 
 0.490
PPP2CA
Serine/threonine-protein phosphatase.
    
 0.484
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.