Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MICU1Uncharacterized protein. (482 aa)    
Predicted Functional Partners:
MCU
Mitochondrial calcium uniporter.
    
 0.989
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.983
MICU2
Mitochondrial calcium uptake 2.
    
0.982
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
    
 0.972
MICU3
Mitochondrial calcium uptake family member 3.
   
0.965
TIMM13
Translocase of inner mitochondrial membrane 13; Belongs to the small Tim family.
      
 0.759
NDUFA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
      
 0.728
NDUFB7
NADH:ubiquinone oxidoreductase subunit B7.
      
 0.727
PHB2
Prohibitin.
    
 0.722
COX11
Cytochrome c oxidase copper chaperone COX11.
      
 0.720
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
Server load: low (28%) [HD]