STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMSB4XThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)    
Predicted Functional Partners:
ACTB
Actin beta.
   
 0.826
LOC105540050
LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
    
 
 0.501
PFN4
Profilin; Belongs to the profilin family.
   
 
 0.451
PFN3
Profilin; Belongs to the profilin family.
   
 
 0.451
ILK
Integrin linked kinase.
    
 
 0.447
ENSMLEP00000039500
Profilin; Belongs to the profilin family.
   
 
 0.409
ACTG1
Actin gamma 1.
   
 0.401
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.