STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APLFAprataxin and PNKP like factor. (511 aa)    
Predicted Functional Partners:
XRCC5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
    
 
 0.944
XRCC6
X-ray repair cross complementing 6.
    
 
 0.933
XRCC1
X-ray repair cross complementing 1.
    
 
 0.897
LIG4
DNA ligase.
    
 
 0.857
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.818
PARP1
Poly [ADP-ribose] polymerase.
    
 
 0.811
LIG3
DNA ligase.
    
 
 0.791
LOC105554539
DNA_pol_B_thumb domain-containing protein.
    
 
 0.783
TDP1
Tyrosyl-DNA phosphodiesterase 1.
    
 
 0.747
PARP2
Poly [ADP-ribose] polymerase.
    
 
 0.698
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.