STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)    
Predicted Functional Partners:
BLNK
B cell linker.
   
 
 0.994
SH3BP2
SH3 domain binding protein 2.
   
 0.994
TXK
Tyrosine-protein kinase.
   
 0.993
SYK
Tyrosine-protein kinase.
   
 0.977
LCP2
Lymphocyte cytosolic protein 2.
   
 0.968
RAC2
Rac family small GTPase 2.
   
 0.958
ZAP70
Tyrosine-protein kinase.
   
 0.947
CD19
CD19 molecule.
   
 0.929
RAC3
Rac family small GTPase 3.
   
 0.927
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
0.921
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.