STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHCR77-dehydrocholesterol reductase. (475 aa)    
Predicted Functional Partners:
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.995
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.976
DHCR24
24-dehydrocholesterol reductase.
   
 0.969
SQLE
Squalene epoxidase.
   
 
 0.957
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 0.949
MSMO1
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 0.945
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 
 0.941
CYP46A1
Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.920
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 
 0.904
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
 
 0.904
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.