STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACAP2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (768 aa)    
Predicted Functional Partners:
RAB35
RAB35, member RAS oncogene family.
    
 
 0.870
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
0.745
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 
0.745
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
    0.714
BANP
BTG3 associated nuclear protein.
      
 0.612
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 0.611
ARFGAP1
ADP ribosylation factor GTPase activating protein 1.
   
0.565
FMNL2
Formin like 2.
      
 0.547
AKAP11
A-kinase anchoring protein 11.
   
    0.509
OCRL
OCRL inositol polyphosphate-5-phosphatase.
    
 
 0.507
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.