STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXW8F-box and WD repeat domain containing 8. (492 aa)    
Predicted Functional Partners:
CUL7
Cullin 7; Belongs to the cullin family.
   
 0.988
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.964
ENSMLEP00000008311
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.946
RBX1
RING-type domain-containing protein.
    
 0.941
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.914
ENSMLEP00000022706
Zf-rbx1 domain-containing protein.
    
 0.912
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.773
COQ9
Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
    
 0.751
FBXO4
F-box protein 4.
    
 0.622
SKP2
S-phase kinase associated protein 2.
    
 0.620
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.