STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTK6Tyrosine-protein kinase. (451 aa)    
Predicted Functional Partners:
KHDRBS1
KH RNA binding domain containing, signal transduction associated 1.
    
 0.878
CBL
Cbl proto-oncogene.
    
 0.851
SH2D1A
SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.
   
 0.837
STAP2
Signal transducing adaptor family member 2.
    
 0.823
LOC105548340
Uncharacterized protein.
    
 0.810
BCAR1
BCAR1 scaffold protein, Cas family member.
   
 0.791
ITSN2
Intersectin 2.
   
 0.762
AKT1
Non-specific serine/threonine protein kinase.
  
0.720
LYN
Tyrosine-protein kinase.
  
0.712
ZNF44
Zinc finger protein 44.
    
 0.699
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.