Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTK6Tyrosine-protein kinase. (451 aa)    
Predicted Functional Partners:
KHDRBS1
KH RNA binding domain containing, signal transduction associated 1.
    
 0.969
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.964
STAP2
Signal transducing adaptor family member 2.
    
 0.962
CBL
Cbl proto-oncogene.
    
 0.911
PTPN1
Tyrosine-protein phosphatase non-receptor type.
   
 0.908
AKT1
Non-specific serine/threonine protein kinase.
  
 
0.907
ARHGAP35
Rho GTPase activating protein 35.
    
 0.900
EGFR
Receptor protein-tyrosine kinase.
    
 0.862
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 0.856
PXN
Paxillin.
    
 0.839
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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