Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MMEL1Membrane metalloendopeptidase like 1. (618 aa)    
Predicted Functional Partners:
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
      
 0.688
TDRD7
Tudor domain containing 7.
    
   0.631
MAP2K2
Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
    
   0.598
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
    
   0.598
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
    
   0.598
ENSMLEP00000024805
Protein kinase domain-containing protein.
    
   0.598
PSENEN
Presenilin enhancer, gamma-secretase subunit.
      
 0.578
EDN1
Endothelin 1.
     
 0.576
NCSTN
Nicastrin.
      
 0.574
EDN3
Endothelin 3.
    
 0.572
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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