STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1L2Signal induced proliferation associated 1 like 2. (1722 aa)    
Predicted Functional Partners:
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.902
ENSMLEP00000004779
Uncharacterized protein.
    
 0.809
RAP1B
Uncharacterized protein.
    
 0.809
LOC105553738
Uncharacterized protein.
    
 0.809
NEFL
Neurofilament light; Belongs to the intermediate filament family.
      
 0.607
KLHDC8B
Kelch domain containing 8B.
   
  
 0.487
PRR35
Proline rich 35.
      
 0.485
WDR27
WD repeat domain 27.
 
  
 
 0.485
MBP
Myelin basic protein.
   
  
 0.485
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
      
 0.483
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.