Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC105537828Uncharacterized protein. (149 aa)    
Predicted Functional Partners:
LOC105554353
Heparanase 2 (inactive).
 
      0.899
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.736
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.539
HPSE
Heparanase.
     
 0.518
GPC5
Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
  0.501
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
  0.501
GPC1
Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.494
LRIG2
Leucine rich repeats and immunoglobulin like domains 2.
      
 0.459
SDC4
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.445
AGRN
Agrin.
     
 0.422
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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