HINT3 protein (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

HINT3

Histidine triad nucleotide binding protein 3. (148 aa)

Predicted Functional Partners:

FBXO15

0.642

DMAC2L

0.586

ENSMLEP00000024203

0.586

FAM20C

0.582

MED22

0.514

TAF1D

0.447

OTULIN

0.436

ENOPH1

0.430

PFDN6

0.416

HINT2

0.401

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DMAC2L	HINT3	ENSMLEP00000015013	ENSMLEP00000010099	Distal membrane arm assembly complex 2 like.	Histidine triad nucleotide binding protein 3.	0.586
ENOPH1	FAM20C	ENSMLEP00000015383	ENSMLEP00000000481	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	FAM20C golgi associated secretory pathway kinase.	0.518
ENOPH1	HINT3	ENSMLEP00000015383	ENSMLEP00000010099	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Histidine triad nucleotide binding protein 3.	0.430
ENOPH1	OTULIN	ENSMLEP00000015383	ENSMLEP00000012037	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	OTU deubiquitinase with linear linkage specificity.	0.607
ENSMLEP00000024203	HINT3	ENSMLEP00000024203	ENSMLEP00000010099	Uncharacterized protein.	Histidine triad nucleotide binding protein 3.	0.586
FAM20C	ENOPH1	ENSMLEP00000000481	ENSMLEP00000015383	FAM20C golgi associated secretory pathway kinase.	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	0.518
FAM20C	HINT3	ENSMLEP00000000481	ENSMLEP00000010099	FAM20C golgi associated secretory pathway kinase.	Histidine triad nucleotide binding protein 3.	0.582
FAM20C	OTULIN	ENSMLEP00000000481	ENSMLEP00000012037	FAM20C golgi associated secretory pathway kinase.	OTU deubiquitinase with linear linkage specificity.	0.528
FBXO15	HINT3	ENSMLEP00000031509	ENSMLEP00000010099	F-box protein 15.	Histidine triad nucleotide binding protein 3.	0.642
HINT2	HINT3	ENSMLEP00000010419	ENSMLEP00000010099	Histidine triad nucleotide binding protein 2.	Histidine triad nucleotide binding protein 3.	0.401
HINT2	TAF1D	ENSMLEP00000010419	ENSMLEP00000030896	Histidine triad nucleotide binding protein 2.	TATA-box binding protein associated factor, RNA polymerase I subunit D.	0.871
HINT3	DMAC2L	ENSMLEP00000010099	ENSMLEP00000015013	Histidine triad nucleotide binding protein 3.	Distal membrane arm assembly complex 2 like.	0.586
HINT3	ENOPH1	ENSMLEP00000010099	ENSMLEP00000015383	Histidine triad nucleotide binding protein 3.	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	0.430
HINT3	ENSMLEP00000024203	ENSMLEP00000010099	ENSMLEP00000024203	Histidine triad nucleotide binding protein 3.	Uncharacterized protein.	0.586
HINT3	FAM20C	ENSMLEP00000010099	ENSMLEP00000000481	Histidine triad nucleotide binding protein 3.	FAM20C golgi associated secretory pathway kinase.	0.582
HINT3	FBXO15	ENSMLEP00000010099	ENSMLEP00000031509	Histidine triad nucleotide binding protein 3.	F-box protein 15.	0.642
HINT3	HINT2	ENSMLEP00000010099	ENSMLEP00000010419	Histidine triad nucleotide binding protein 3.	Histidine triad nucleotide binding protein 2.	0.401
HINT3	MED22	ENSMLEP00000010099	ENSMLEP00000026082	Histidine triad nucleotide binding protein 3.	Mediator complex subunit 22.	0.514
HINT3	OTULIN	ENSMLEP00000010099	ENSMLEP00000012037	Histidine triad nucleotide binding protein 3.	OTU deubiquitinase with linear linkage specificity.	0.436
HINT3	PFDN6	ENSMLEP00000010099	ENSMLEP00000018143	Histidine triad nucleotide binding protein 3.	Prefoldin subunit 6.	0.416