STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD27CD27 molecule. (260 aa)    
Predicted Functional Partners:
CD70
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
 0.999
CD38
CD38 molecule.
   
  
 0.894
CD69
CD69 molecule.
   
  
 0.861
CD4
CD4 molecule.
   
  
 0.858
CD28
CD28 molecule.
   
  
 0.820
CCR7
C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.805
CD19
CD19 molecule.
   
  
 0.742
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 
 0.726
IL2
Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.
  
   
 0.665
CD40
CD40 molecule.
   
  
 0.631
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.