node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSMLEP00000029690 | FLAD1 | ENSMLEP00000029690 | ENSMLEP00000010221 | FAD_binding_2 domain-containing protein. | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | 0.928 |
ENSMLEP00000029690 | PAPSS1 | ENSMLEP00000029690 | ENSMLEP00000036408 | FAD_binding_2 domain-containing protein. | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. | 0.899 |
ENSMLEP00000029690 | PAPSS2 | ENSMLEP00000029690 | ENSMLEP00000004059 | FAD_binding_2 domain-containing protein. | 3'-phosphoadenosine 5'-phosphosulfate synthase 2. | 0.899 |
ENSMLEP00000029690 | SUOX | ENSMLEP00000029690 | ENSMLEP00000040734 | FAD_binding_2 domain-containing protein. | Sulfite oxidase. | 0.888 |
FLAD1 | ENSMLEP00000029690 | ENSMLEP00000010221 | ENSMLEP00000029690 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | FAD_binding_2 domain-containing protein. | 0.928 |
FLAD1 | MTRR | ENSMLEP00000010221 | ENSMLEP00000032931 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. | 0.921 |
FLAD1 | NDOR1 | ENSMLEP00000010221 | ENSMLEP00000021971 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.921 |
FLAD1 | NOS1 | ENSMLEP00000010221 | ENSMLEP00000012036 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.921 |
FLAD1 | NOS2 | ENSMLEP00000010221 | ENSMLEP00000027860 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.921 |
FLAD1 | NOS3 | ENSMLEP00000010221 | ENSMLEP00000014301 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | Nitric oxide synthase; Produces nitric oxide (NO). | 0.921 |
FLAD1 | PAPSS1 | ENSMLEP00000010221 | ENSMLEP00000036408 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. | 0.996 |
FLAD1 | PAPSS2 | ENSMLEP00000010221 | ENSMLEP00000004059 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | 3'-phosphoadenosine 5'-phosphosulfate synthase 2. | 0.996 |
FLAD1 | POR | ENSMLEP00000010221 | ENSMLEP00000017590 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.921 |
FLAD1 | SUOX | ENSMLEP00000010221 | ENSMLEP00000040734 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | Sulfite oxidase. | 0.980 |
MTRR | FLAD1 | ENSMLEP00000032931 | ENSMLEP00000010221 | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | 0.921 |
MTRR | PAPSS1 | ENSMLEP00000032931 | ENSMLEP00000036408 | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. | 0.792 |
MTRR | PAPSS2 | ENSMLEP00000032931 | ENSMLEP00000004059 | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. | 3'-phosphoadenosine 5'-phosphosulfate synthase 2. | 0.791 |
MTRR | SUOX | ENSMLEP00000032931 | ENSMLEP00000040734 | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. | Sulfite oxidase. | 0.916 |
NDOR1 | FLAD1 | ENSMLEP00000021971 | ENSMLEP00000010221 | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | 0.921 |
NDOR1 | PAPSS1 | ENSMLEP00000021971 | ENSMLEP00000036408 | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. | 0.791 |