STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (142 aa)    
Predicted Functional Partners:
SLC25A31
Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 0.957
SLC25A4
Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 0.952
VDAC1
Voltage dependent anion channel 1.
   
 0.952
VDAC2
Voltage dependent anion channel 2.
   
 0.941
VDAC3
Voltage dependent anion channel 3.
   
 0.940
ENSMLEP00000022425
Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 0.935
SLC25A5
Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 0.926
ENSMLEP00000006706
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
 
 0.908
PPID
Uncharacterized protein.
  
 
0.906
CCR5
C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity).
   
  0.891
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.