Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEFB127Defensin beta 127. (93 aa)    
Predicted Functional Partners:
ACTR1B
Actin related protein 1B.
    
  0.844
DCTN6
Dynactin subunit 6.
    
   0.843
DCTN5
Dynactin subunit 5.
    
   0.843
ACTR10
Actin related protein 10; Belongs to the actin family.
    
  0.840
DCTN4
Dynactin subunit 4.
    
   0.833
DCTN3
Dynactin subunit 3.
    
   0.806
DEFB134
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.796
ACTR1A
Actin related protein 1A.
    
  0.718
DEFB114
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.712
DCTN2
Dynactin subunit 2.
    
   0.710
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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