STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOTCH3Notch receptor 3. (2185 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.992
JAG2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.958
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.945
MAML1
Mastermind like transcriptional coactivator 1.
   
 0.944
DLL3
Delta like canonical Notch ligand 3.
     
0.943
MAML3
Mastermind like transcriptional coactivator 3.
    
 0.927
MAML2
Mastermind like transcriptional coactivator 2.
    
 0.926
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.923
DTX1
Deltex E3 ubiquitin ligase 1.
    
 0.920
DTX3L
Deltex E3 ubiquitin ligase 3L.
    
 0.919
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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