node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAMTS3 | CX3CL1 | ENSMLEP00000015712 | ENSMLEP00000007552 | ADAM metallopeptidase with thrombospondin type 1 motif 3. | C-X3-C motif chemokine ligand 1. | 0.494 |
ADAMTS3 | GET3 | ENSMLEP00000015712 | ENSMLEP00000036675 | ADAM metallopeptidase with thrombospondin type 1 motif 3. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.635 |
ADAMTS3 | TMEM86A | ENSMLEP00000015712 | ENSMLEP00000013321 | ADAM metallopeptidase with thrombospondin type 1 motif 3. | Transmembrane protein 86A. | 0.700 |
ADAMTS3 | TSPAN2 | ENSMLEP00000015712 | ENSMLEP00000024248 | ADAM metallopeptidase with thrombospondin type 1 motif 3. | Tetraspanin. | 0.524 |
ADAMTS3 | VIPR1 | ENSMLEP00000015712 | ENSMLEP00000004418 | ADAM metallopeptidase with thrombospondin type 1 motif 3. | Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.485 |
C11orf54 | TMEM86A | ENSMLEP00000022043 | ENSMLEP00000013321 | Chromosome 11 open reading frame 54. | Transmembrane protein 86A. | 0.485 |
CX3CL1 | ADAMTS3 | ENSMLEP00000007552 | ENSMLEP00000015712 | C-X3-C motif chemokine ligand 1. | ADAM metallopeptidase with thrombospondin type 1 motif 3. | 0.494 |
CX3CL1 | GET3 | ENSMLEP00000007552 | ENSMLEP00000036675 | C-X3-C motif chemokine ligand 1. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.495 |
CX3CL1 | TMEM86A | ENSMLEP00000007552 | ENSMLEP00000013321 | C-X3-C motif chemokine ligand 1. | Transmembrane protein 86A. | 0.483 |
CX3CL1 | TSPAN2 | ENSMLEP00000007552 | ENSMLEP00000024248 | C-X3-C motif chemokine ligand 1. | Tetraspanin. | 0.435 |
CX3CL1 | VIPR1 | ENSMLEP00000007552 | ENSMLEP00000004418 | C-X3-C motif chemokine ligand 1. | Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.549 |
DLST | TMEM86A | ENSMLEP00000026652 | ENSMLEP00000013321 | Dihydrolipoamide S-succinyltransferase. | Transmembrane protein 86A. | 0.482 |
GET3 | ADAMTS3 | ENSMLEP00000036675 | ENSMLEP00000015712 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | ADAM metallopeptidase with thrombospondin type 1 motif 3. | 0.635 |
GET3 | CX3CL1 | ENSMLEP00000036675 | ENSMLEP00000007552 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | C-X3-C motif chemokine ligand 1. | 0.495 |
GET3 | PTGS1 | ENSMLEP00000036675 | ENSMLEP00000005632 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Prostaglandin-endoperoxide synthase 1. | 0.485 |
GET3 | TMEM86A | ENSMLEP00000036675 | ENSMLEP00000013321 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Transmembrane protein 86A. | 0.704 |
GET3 | TSPAN2 | ENSMLEP00000036675 | ENSMLEP00000024248 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Tetraspanin. | 0.538 |
GET3 | VIPR1 | ENSMLEP00000036675 | ENSMLEP00000004418 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.537 |
NXPH2 | TMEM86A | ENSMLEP00000029820 | ENSMLEP00000013321 | Neurexophilin; May be signaling molecules that resemble neuropeptides. | Transmembrane protein 86A. | 0.483 |
PLB1 | PTGS1 | ENSMLEP00000027140 | ENSMLEP00000005632 | Phospholipase B1. | Prostaglandin-endoperoxide synthase 1. | 0.761 |