STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)    
Predicted Functional Partners:
LY96
Lymphocyte antigen 96.
   
 0.999
TICAM2
Toll like receptor adaptor molecule 2.
   
 0.998
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
0.997
TIRAP
TIR domain containing adaptor protein.
   
 0.995
TICAM1
Toll like receptor adaptor molecule 1.
   
 0.986
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.985
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.973
CD14
CD14 molecule.
   
 0.969
TLR2
Toll-like receptor.
   
0.966
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
 0.956
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
Server load: low (12%) [HD]