node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFF4 | MED13 | ENSMLEP00000009627 | ENSMLEP00000031568 | AF4/FMR2 family member 4. | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.793 |
AFF4 | RC3H2 | ENSMLEP00000009627 | ENSMLEP00000019293 | AF4/FMR2 family member 4. | Ring finger and CCCH-type domains 2. | 0.745 |
CEP350 | MED13 | ENSMLEP00000035212 | ENSMLEP00000031568 | Centrosomal protein 350. | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.573 |
CEP350 | MYSM1 | ENSMLEP00000035212 | ENSMLEP00000035781 | Centrosomal protein 350. | Myb like, SWIRM and MPN domains 1. | 0.501 |
CEP350 | PHIP | ENSMLEP00000035212 | ENSMLEP00000025642 | Centrosomal protein 350. | Pleckstrin homology domain interacting protein. | 0.748 |
CEP350 | RC3H2 | ENSMLEP00000035212 | ENSMLEP00000019293 | Centrosomal protein 350. | Ring finger and CCCH-type domains 2. | 0.717 |
CEP350 | SMG1 | ENSMLEP00000035212 | ENSMLEP00000024421 | Centrosomal protein 350. | SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. | 0.795 |
CEP350 | UBR1 | ENSMLEP00000035212 | ENSMLEP00000030226 | Centrosomal protein 350. | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. | 0.714 |
CNOT1 | RC3H1 | ENSMLEP00000035033 | ENSMLEP00000026513 | CCR4-NOT transcription complex subunit 1. | Ring finger and CCCH-type domains 1. | 0.775 |
CNOT1 | RC3H2 | ENSMLEP00000035033 | ENSMLEP00000019293 | CCR4-NOT transcription complex subunit 1. | Ring finger and CCCH-type domains 2. | 0.752 |
CNOT1 | TRIP12 | ENSMLEP00000035033 | ENSMLEP00000006329 | CCR4-NOT transcription complex subunit 1. | Thyroid hormone receptor interactor 12. | 0.869 |
MED13 | AFF4 | ENSMLEP00000031568 | ENSMLEP00000009627 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | AF4/FMR2 family member 4. | 0.793 |
MED13 | CEP350 | ENSMLEP00000031568 | ENSMLEP00000035212 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Centrosomal protein 350. | 0.573 |
MED13 | RC3H2 | ENSMLEP00000031568 | ENSMLEP00000019293 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Ring finger and CCCH-type domains 2. | 0.723 |
MED13 | SMG1 | ENSMLEP00000031568 | ENSMLEP00000024421 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. | 0.454 |
MED13 | UBR1 | ENSMLEP00000031568 | ENSMLEP00000030226 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. | 0.542 |
MYSM1 | CEP350 | ENSMLEP00000035781 | ENSMLEP00000035212 | Myb like, SWIRM and MPN domains 1. | Centrosomal protein 350. | 0.501 |
MYSM1 | PHIP | ENSMLEP00000035781 | ENSMLEP00000025642 | Myb like, SWIRM and MPN domains 1. | Pleckstrin homology domain interacting protein. | 0.846 |
MYSM1 | RC3H1 | ENSMLEP00000035781 | ENSMLEP00000026513 | Myb like, SWIRM and MPN domains 1. | Ring finger and CCCH-type domains 1. | 0.750 |
MYSM1 | RC3H2 | ENSMLEP00000035781 | ENSMLEP00000019293 | Myb like, SWIRM and MPN domains 1. | Ring finger and CCCH-type domains 2. | 0.821 |