STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIGLEC11Uncharacterized protein. (437 aa)    
Predicted Functional Partners:
ENSMLEP00000023166
Uncharacterized protein.
      
 0.483
IL4
Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.
  
   
 0.468
HAVCR2
Hepatitis A virus cellular receptor 2.
  
 
 0.464
CD22
CD22 molecule.
  
 
0.441
FCMR
Fc fragment of IgM receptor.
  
 0.440
CDH24
Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins.
    
 
 0.431
CD300LF
CD300 molecule like family member f.
  
 0.422
MCEMP1
Mast cell expressed membrane protein 1.
  
 
  0.420
CCDC136
Coiled-coil domain containing 136.
  
  
 0.414
TEX101
Testis expressed 101.
  
  
  0.414
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.