STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRASNRAS proto-oncogene, GTPase. (189 aa)    
Predicted Functional Partners:
CALML4
Calmodulin like 4.
   
 0.993
IFNGR1
Interferon gamma receptor 1.
   
 0.992
RPS6KA3
Ribosomal protein S6 kinase.
   
 0.992
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.986
NF1
Neurofibromin 1.
    
 0.980
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
    
 0.976
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.976
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.973
ENSMLEP00000012301
Protein kinase domain-containing protein.
   
 0.972
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.972
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.