STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3SEM1_GORGOCathepsin L; Belongs to the peptidase C1 family. (333 aa)    
Predicted Functional Partners:
CSTA
Cystatin A; Belongs to the cystatin family.
   
 0.969
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
  
0.965
BCL2
BCL2 apoptosis regulator.
   
 
 0.916
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
 0.909
G3R7S6_GORGO
CD74 molecule.
   
 0.909
BCL2L1
BCL2 like 1.
     
 0.907
CTSK
Cathepsin K; Belongs to the peptidase C1 family.
  
 
0.840
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
     
 0.741
ZNF782
Zinc finger protein 782.
    
 
 0.732
CTSH
Cathepsin H; Belongs to the peptidase C1 family.
  
0.709
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.