STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (720 aa)    
Predicted Functional Partners:
MTR
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 0.974
FREM3
FRAS1 related extracellular matrix 3.
   
  
 0.917
PROKR2
Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.915
IGFBP7
Insulin like growth factor binding protein 7.
      
 0.897
CBS
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.897
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family.
      
 0.880
ENSGGOP00000042938
Checkpoint protein; Belongs to the HUS1 family.
      
 0.871
ENSGGOP00000030107
Metabolism of cobalamin associated D.
     
 0.869
FLAD1
FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
  
 
 0.818
MTHFR
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.808
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.