STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (293 aa)    
Predicted Functional Partners:
SPINK5
Serine peptidase inhibitor, Kazal type 5.
   
 0.965
SPINK9
Kazal-like domain-containing protein.
    
 0.964
G3QGF0_GORGO
Kallikrein related peptidase 8; Belongs to the peptidase S1 family.
  
 
 
0.911
G3RY68_GORGO
Chymotrypsin like elastase 2A; Belongs to the peptidase S1 family.
  
 
 
0.869
G3SJ49_GORGO
Kallikrein related peptidase 7; Belongs to the peptidase S1 family.
  
 
 
0.859
PGC
Progastricsin; Belongs to the peptidase A1 family.
    
 0.812
KRT77
Keratin 77; Belongs to the intermediate filament family.
   
 0.727
SERPINB4
Serpin family B member 4; Belongs to the serpin family.
   
 0.701
ST14
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family.
  
  
0.665
DEFB126
Beta-defensin 126; Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other s [...]
      
 0.655
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.