STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3QFN1_GORGOKatanin catalytic subunit A1; Belongs to the AAA ATPase family. (415 aa)    
Predicted Functional Partners:
KATNB1
Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...]
   
 0.978
KATNBL1
Katanin_con80 domain-containing protein.
   
 0.885
ENTHD1
ENTH domain containing 1.
   
  
 0.874
ZNHIT2
Zinc finger HIT-type containing 2.
   
  
 0.871
SLITRK1
SLIT and NTRK like family member 1.
    
 
 0.860
KIF18A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
     
 0.849
ENSGGOP00000028845
Katanin_con80 domain-containing protein.
   
 
 0.827
PRDM10
PR/SET domain 10.
    
 0.810
G3RPJ8_GORGO
Proteasome 26S subunit, non-ATPase 6.
   
 0.720
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5.
    
 
 0.711
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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