Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ZFP62ZFP62 zinc finger protein. (900 aa)    
Predicted Functional Partners:
PUM3
Pumilio RNA binding family member 3.
    
   0.716
FSD1L
Fibronectin type III and SPRY domain containing 1 like.
   
 0.695
ENSGGOP00000034376
RNA binding motif protein 34.
    
   0.676
RRP8
Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...]
    
   0.660
RPL14
Ribosomal_L14e domain-containing protein.
    
   0.612
PPAN
Peter pan homolog.
    
 
 0.598
RPL37A
Ribosomal protein L37a.
    
   0.589
CWF19L2
CWF19 like cell cycle control factor 2.
      
 0.585
PGM2L1
Phosphoglucomutase 2 like 1.
    
 
 0.569
SLC17A6
Solute carrier family 17 member 6.
      
 0.567
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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