PRDX5 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PRDX5

Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa)

Predicted Functional Partners:

PRDX3

0.983

PRDX1

0.944

TXN2

0.926

PRDX2

0.924

ENSGGOP00000029619

0.901

ENSGGOP00000035220

0.886

TXN

0.860

PRDX4

0.853

SOD1

0.838

SOD2

0.830

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGGOP00000029619	ENSGGOP00000035220	ENSGGOP00000029619	ENSGGOP00000035220	Thioredoxin domain-containing protein.	Thioredoxin domain-containing protein.	0.905
ENSGGOP00000029619	PRDX2	ENSGGOP00000029619	ENSGGOP00000021801	Thioredoxin domain-containing protein.	Peroxiredoxin 2.	0.905
ENSGGOP00000029619	PRDX3	ENSGGOP00000029619	ENSGGOP00000027935	Thioredoxin domain-containing protein.	Peroxiredoxin 3.	0.727
ENSGGOP00000029619	PRDX4	ENSGGOP00000029619	ENSGGOP00000020541	Thioredoxin domain-containing protein.	Peroxiredoxin 4.	0.850
ENSGGOP00000029619	PRDX5	ENSGGOP00000029619	ENSGGOP00000001320	Thioredoxin domain-containing protein.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.901
ENSGGOP00000029619	SOD1	ENSGGOP00000029619	ENSGGOP00000043154	Thioredoxin domain-containing protein.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.688
ENSGGOP00000029619	SOD2	ENSGGOP00000029619	ENSGGOP00000008027	Thioredoxin domain-containing protein.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.559
ENSGGOP00000029619	TXN	ENSGGOP00000029619	ENSGGOP00000006774	Thioredoxin domain-containing protein.	Thioredoxin; Belongs to the thioredoxin family.	0.929
ENSGGOP00000029619	TXN2	ENSGGOP00000029619	ENSGGOP00000039952	Thioredoxin domain-containing protein.	Thioredoxin 2.	0.761
ENSGGOP00000035220	ENSGGOP00000029619	ENSGGOP00000035220	ENSGGOP00000029619	Thioredoxin domain-containing protein.	Thioredoxin domain-containing protein.	0.905
ENSGGOP00000035220	PRDX1	ENSGGOP00000035220	ENSGGOP00000030079	Thioredoxin domain-containing protein.	Peroxiredoxin 1.	0.949
ENSGGOP00000035220	PRDX3	ENSGGOP00000035220	ENSGGOP00000027935	Thioredoxin domain-containing protein.	Peroxiredoxin 3.	0.538
ENSGGOP00000035220	PRDX4	ENSGGOP00000035220	ENSGGOP00000020541	Thioredoxin domain-containing protein.	Peroxiredoxin 4.	0.669
ENSGGOP00000035220	PRDX5	ENSGGOP00000035220	ENSGGOP00000001320	Thioredoxin domain-containing protein.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.886
ENSGGOP00000035220	SOD1	ENSGGOP00000035220	ENSGGOP00000043154	Thioredoxin domain-containing protein.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.641
ENSGGOP00000035220	SOD2	ENSGGOP00000035220	ENSGGOP00000008027	Thioredoxin domain-containing protein.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.559
ENSGGOP00000035220	TXN	ENSGGOP00000035220	ENSGGOP00000006774	Thioredoxin domain-containing protein.	Thioredoxin; Belongs to the thioredoxin family.	0.900
ENSGGOP00000035220	TXN2	ENSGGOP00000035220	ENSGGOP00000039952	Thioredoxin domain-containing protein.	Thioredoxin 2.	0.690
PRDX1	ENSGGOP00000035220	ENSGGOP00000030079	ENSGGOP00000035220	Peroxiredoxin 1.	Thioredoxin domain-containing protein.	0.949
PRDX1	PRDX2	ENSGGOP00000030079	ENSGGOP00000021801	Peroxiredoxin 1.	Peroxiredoxin 2.	0.949

page 1 of 6

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About