STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa)    
Predicted Functional Partners:
PRDX3
Peroxiredoxin 3.
   
 0.962
TXN
Thioredoxin; Belongs to the thioredoxin family.
   
 0.905
PRDX1
Peroxiredoxin 1.
   
 0.894
ENSGGOP00000029619
Thioredoxin domain-containing protein.
   
 0.839
PRDX2
Peroxiredoxin 2.
   
 0.837
TXN2
Thioredoxin 2.
   
 0.829
NME8
NME/NM23 family member 8.
   
 0.824
PRDX4
Peroxiredoxin 4.
   
 0.809
TXNDC8
Thioredoxin domain containing 8.
   
 0.798
TXNDC2
Thioredoxin domain-containing protein.
   
 0.788
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.