STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1SComplement C1s; Belongs to the peptidase S1 family. (780 aa)    
Predicted Functional Partners:
SERPING1
Serpin family G member 1; Belongs to the serpin family.
   
 0.999
C1R
Complement C1r; Belongs to the peptidase S1 family.
  
0.999
C1QC
Complement C1q C chain.
   
 
 0.977
ENSGGOP00000044488
Uncharacterized protein.
   
 0.975
C1RL
Complement C1r subcomponent like; Belongs to the peptidase S1 family.
  
0.971
C1QB
Complement C1q B chain.
   
 0.955
G3RQR5_GORGO
Ig-like domain-containing protein.
    
  0.921
MBL2
Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
   
 0.849
C3
Complement C3.
   
 0.827
G3R3G6_GORGO
Complement C1q A chain.
   
 0.811
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.