HECTD3 protein (Gorilla gorilla) - STRING interaction network

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Score

HECTD3

HECT domain E3 ubiquitin protein ligase 3. (861 aa)

Predicted Functional Partners:

TRIP12

0.751

UBA52

0.640

PGM2

0.599

FAU

0.580

G3S6C1_GORGO

0.580

PGM2L1

0.534

ENSGGOP00000043200

0.513

ATG7

0.478

ZFAND4

0.458

UBD

0.458

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG7	FAU	ENSGGOP00000003435	ENSGGOP00000002675	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.507
ATG7	G3S6C1_GORGO	ENSGGOP00000003435	ENSGGOP00000023628	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-like domain-containing protein.	0.507
ATG7	HECTD3	ENSGGOP00000003435	ENSGGOP00000001508	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	HECT domain E3 ubiquitin protein ligase 3.	0.478
ATG7	TRIP12	ENSGGOP00000003435	ENSGGOP00000045047	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Thyroid hormone receptor interactor 12.	0.875
ATG7	UBA52	ENSGGOP00000003435	ENSGGOP00000004534	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-like domain-containing protein.	0.795
ATG7	UBD	ENSGGOP00000003435	ENSGGOP00000008531	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin D.	0.501
ATG7	ZFAND4	ENSGGOP00000003435	ENSGGOP00000003481	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Zinc finger AN1-type containing 4.	0.532
ENSGGOP00000043200	FAU	ENSGGOP00000043200	ENSGGOP00000002675	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.477
ENSGGOP00000043200	G3S6C1_GORGO	ENSGGOP00000043200	ENSGGOP00000023628	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	Ubiquitin-like domain-containing protein.	0.477
ENSGGOP00000043200	HECTD3	ENSGGOP00000043200	ENSGGOP00000001508	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	HECT domain E3 ubiquitin protein ligase 3.	0.513
ENSGGOP00000043200	TRIP12	ENSGGOP00000043200	ENSGGOP00000045047	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	Thyroid hormone receptor interactor 12.	0.448
ENSGGOP00000043200	UBA52	ENSGGOP00000043200	ENSGGOP00000004534	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	Ubiquitin-like domain-containing protein.	0.662
ENSGGOP00000043200	UBD	ENSGGOP00000043200	ENSGGOP00000008531	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	Ubiquitin D.	0.477
ENSGGOP00000043200	ZFAND4	ENSGGOP00000043200	ENSGGOP00000003481	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	Zinc finger AN1-type containing 4.	0.477
FAU	ATG7	ENSGGOP00000002675	ENSGGOP00000003435	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.507
FAU	ENSGGOP00000043200	ENSGGOP00000002675	ENSGGOP00000043200	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	0.477
FAU	G3S6C1_GORGO	ENSGGOP00000002675	ENSGGOP00000023628	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like domain-containing protein.	0.989
FAU	HECTD3	ENSGGOP00000002675	ENSGGOP00000001508	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	HECT domain E3 ubiquitin protein ligase 3.	0.580
FAU	TRIP12	ENSGGOP00000002675	ENSGGOP00000045047	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Thyroid hormone receptor interactor 12.	0.817
FAU	UBA52	ENSGGOP00000002675	ENSGGOP00000004534	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like domain-containing protein.	0.996