close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
URODUroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (367 aa)    
Predicted Functional Partners:
PPOX
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.992
CPOX
Coproporphyrinogen oxidase.
  
 0.990
HMBS
Hydroxymethylbilane synthase.
 0.943
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
 
  
 0.908
G3R707_GORGO
Uroporphyrinogen III synthase.
  
 
 0.883
ALAD
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.798
TYW1
tRNA-yW synthesizing protein 1 homolog.
    
  0.719
PLP2
Proteolipid protein 2.
      
 0.629
CDK5RAP1
Uncharacterized protein.
  
 
 0.596
CDKAL1
CDK5 regulatory subunit associated protein 1 like 1.
  
 
 0.596
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.