Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGF2RInsulin like growth factor 2 receptor. (2491 aa)    
Predicted Functional Partners:
M6PR
Mannose-6-phosphate receptor, cation dependent.
     
 0.995
IGF2
Insulin like growth factor 2.
    
 
 0.968
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
    
 
 0.958
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 
 0.958
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.953
PLIN3
Perilipin; Belongs to the perilipin family.
   
 0.875
VPS26A
Uncharacterized protein.
    
 
 0.862
GAK
Cyclin G associated kinase.
   
 
 0.825
VTI1A
Vesicle transport through interaction with t-SNAREs 1A.
   
 0.755
SNX8
Sorting nexin 8.
    
 0.728
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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