STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)    
Predicted Functional Partners:
PDCD1
Programmed cell death 1.
   
 0.999
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
   
 
 0.941
CD80
CD80 molecule.
   
 0.863
CD28
CD28 molecule.
   
 
 0.799
CD86
CD86 molecule.
   
  
 0.797
ICOS
Inducible T cell costimulator.
   
  
 0.795
RGMB
Repulsive guidance molecule BMP co-receptor b.
      
 0.785
B4GAT1
Beta-1,4-glucuronyltransferase 1.
      
 0.727
CORIN
Corin, serine peptidase.
     
 0.713
CD8A
CD8a molecule.
   
  
 0.694
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.