Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRRG2Proline rich and Gla domain 2. (202 aa)    
Predicted Functional Partners:
GGCX
Gamma-glutamyl carboxylase.
    
 
 0.882
YAP1
Uncharacterized protein.
    
 
 0.820
RCN3
Reticulocalbin 3.
      
 0.820
G3RQI9_GORGO
WW domain-containing protein.
    
 
 0.820
PRR12
DUF4211 domain-containing protein.
      
 0.805
ENSGGOP00000046407
Nitric oxide synthase-interacting protein; Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family.
      
 0.778
CSN1S1
Casein alpha s1.
      
 0.720
WWTR1
WW domain containing transcription regulator 1.
    
 
 0.664
NEDD1
NEDD1 gamma-tubulin ring complex targeting factor.
      
 0.548
GPRASP2
G protein-coupled receptor associated sorting protein 2.
      
 0.537
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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