RNF7 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOBEC3G	CUL5	ENSGGOP00000021965	ENSGGOP00000027637	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Cullin 5; Belongs to the cullin family.	0.978
APOBEC3G	ELOB	ENSGGOP00000021965	ENSGGOP00000014931	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Elongin B.	0.965
APOBEC3G	ELOC	ENSGGOP00000021965	ENSGGOP00000002153	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Elongin C; Belongs to the SKP1 family.	0.955
APOBEC3G	ENSGGOP00000045589	ENSGGOP00000021965	ENSGGOP00000045589	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Ubiquitin-like domain-containing protein.	0.505
APOBEC3G	G3R2E6_GORGO	ENSGGOP00000021965	ENSGGOP00000009396	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.944
APOBEC3G	RNF7	ENSGGOP00000021965	ENSGGOP00000001803	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Ring finger protein 7.	0.937
CUL1	CUL5	ENSGGOP00000042961	ENSGGOP00000027637	Cullin domain-containing protein; Belongs to the cullin family.	Cullin 5; Belongs to the cullin family.	0.504
CUL1	ELOB	ENSGGOP00000042961	ENSGGOP00000014931	Cullin domain-containing protein; Belongs to the cullin family.	Elongin B.	0.622
CUL1	ELOC	ENSGGOP00000042961	ENSGGOP00000002153	Cullin domain-containing protein; Belongs to the cullin family.	Elongin C; Belongs to the SKP1 family.	0.769
CUL1	ENSGGOP00000045589	ENSGGOP00000042961	ENSGGOP00000045589	Cullin domain-containing protein; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.491
CUL1	G3R2E6_GORGO	ENSGGOP00000042961	ENSGGOP00000009396	Cullin domain-containing protein; Belongs to the cullin family.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.772
CUL1	NEDD8	ENSGGOP00000042961	ENSGGOP00000015709	Cullin domain-containing protein; Belongs to the cullin family.	NEDD8 ubiquitin like modifier.	0.988
CUL1	RNF7	ENSGGOP00000042961	ENSGGOP00000001803	Cullin domain-containing protein; Belongs to the cullin family.	Ring finger protein 7.	0.972
CUL1	UBE2D3	ENSGGOP00000042961	ENSGGOP00000001352	Cullin domain-containing protein; Belongs to the cullin family.	Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family.	0.753
CUL1	UBXN7	ENSGGOP00000042961	ENSGGOP00000014398	Cullin domain-containing protein; Belongs to the cullin family.	UBX domain-containing protein 7.	0.952
CUL5	APOBEC3G	ENSGGOP00000027637	ENSGGOP00000021965	Cullin 5; Belongs to the cullin family.	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	0.978
CUL5	CUL1	ENSGGOP00000027637	ENSGGOP00000042961	Cullin 5; Belongs to the cullin family.	Cullin domain-containing protein; Belongs to the cullin family.	0.504
CUL5	ELOB	ENSGGOP00000027637	ENSGGOP00000014931	Cullin 5; Belongs to the cullin family.	Elongin B.	0.996
CUL5	ELOC	ENSGGOP00000027637	ENSGGOP00000002153	Cullin 5; Belongs to the cullin family.	Elongin C; Belongs to the SKP1 family.	0.993
CUL5	ENSGGOP00000045589	ENSGGOP00000027637	ENSGGOP00000045589	Cullin 5; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.953