Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIM29Tripartite motif containing 29. (588 aa)    
Predicted Functional Partners:
TRIM11
Tripartite motif containing 11.
    
 
 0.646
G3QSK7_GORGO
T cell receptor associated transmembrane adaptor 1.
      
 0.591
G3RHD0_GORGO
Receptor interacting serine/threonine kinase 4.
   
 0.589
TRIM35
B30.2/SPRY domain-containing protein.
  
 
 
 0.579
RUVBL2
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 
 0.568
TP63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
   
 0.563
TRIM31
Tripartite motif containing 31.
    
 
 0.558
PKP1
Plakophilin 1.
   
 
 0.534
SERPINB5
Serpin family B member 5; Belongs to the serpin family.
   
 
 0.527
KRT5
Keratin 5; Belongs to the intermediate filament family.
   
 0.515
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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