| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DCLRE1A | EME1 | ENSGGOP00000026727 | ENSGGOP00000011019 | DNA cross-link repair 1A. | Essential meiotic structure-specific endonuclease 1. | 0.852 |
| DCLRE1A | ENSGGOP00000034312 | ENSGGOP00000026727 | ENSGGOP00000034312 | DNA cross-link repair 1A. | FA complementation group D2. | 0.866 |
| DCLRE1A | FAN1 | ENSGGOP00000026727 | ENSGGOP00000001911 | DNA cross-link repair 1A. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.840 |
| DCLRE1A | FANCI | ENSGGOP00000026727 | ENSGGOP00000011426 | DNA cross-link repair 1A. | FA complementation group I. | 0.810 |
| DCLRE1A | FANCM | ENSGGOP00000026727 | ENSGGOP00000008369 | DNA cross-link repair 1A. | FA complementation group M. | 0.811 |
| DCLRE1A | SLX1 | ENSGGOP00000026727 | ENSGGOP00000012415 | DNA cross-link repair 1A. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.765 |
| EME1 | DCLRE1A | ENSGGOP00000011019 | ENSGGOP00000026727 | Essential meiotic structure-specific endonuclease 1. | DNA cross-link repair 1A. | 0.852 |
| EME1 | ENSGGOP00000034312 | ENSGGOP00000011019 | ENSGGOP00000034312 | Essential meiotic structure-specific endonuclease 1. | FA complementation group D2. | 0.897 |
| EME1 | FAN1 | ENSGGOP00000011019 | ENSGGOP00000001911 | Essential meiotic structure-specific endonuclease 1. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.821 |
| EME1 | FANCI | ENSGGOP00000011019 | ENSGGOP00000011426 | Essential meiotic structure-specific endonuclease 1. | FA complementation group I. | 0.838 |
| EME1 | FANCM | ENSGGOP00000011019 | ENSGGOP00000008369 | Essential meiotic structure-specific endonuclease 1. | FA complementation group M. | 0.831 |
| EME1 | MLH1 | ENSGGOP00000011019 | ENSGGOP00000015949 | Essential meiotic structure-specific endonuclease 1. | MutL homolog 1. | 0.413 |
| EME1 | SLX1 | ENSGGOP00000011019 | ENSGGOP00000012415 | Essential meiotic structure-specific endonuclease 1. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.951 |
| ENSGGOP00000034312 | DCLRE1A | ENSGGOP00000034312 | ENSGGOP00000026727 | FA complementation group D2. | DNA cross-link repair 1A. | 0.866 |
| ENSGGOP00000034312 | EME1 | ENSGGOP00000034312 | ENSGGOP00000011019 | FA complementation group D2. | Essential meiotic structure-specific endonuclease 1. | 0.897 |
| ENSGGOP00000034312 | FAN1 | ENSGGOP00000034312 | ENSGGOP00000001911 | FA complementation group D2. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.998 |
| ENSGGOP00000034312 | FANCI | ENSGGOP00000034312 | ENSGGOP00000011426 | FA complementation group D2. | FA complementation group I. | 0.999 |
| ENSGGOP00000034312 | FANCM | ENSGGOP00000034312 | ENSGGOP00000008369 | FA complementation group D2. | FA complementation group M. | 0.995 |
| ENSGGOP00000034312 | MLH1 | ENSGGOP00000034312 | ENSGGOP00000015949 | FA complementation group D2. | MutL homolog 1. | 0.749 |
| ENSGGOP00000034312 | SLX1 | ENSGGOP00000034312 | ENSGGOP00000012415 | FA complementation group D2. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.871 |
