STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGGOP00000049868PDZ and LIM domain 3. (364 aa)    
Predicted Functional Partners:
ACTN2
Actinin alpha 2.
   
 
 0.751
SCN8A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.672
SMTNL1
Smoothelin like 1.
   
 
 0.645
EHBP1L1
EH domain binding protein 1 like 1.
   
 0.635
EHBP1
EH domain binding protein 1.
   
 0.635
TTN
Titin.
   
 0.610
ENSGGOP00000047862
PDZ and LIM domain 7.
   
 
0.599
PDLIM4
PDZ and LIM domain 4.
     
0.598
SMTN
Smoothelin.
   
 
 0.595
PDLIM5
PDZ and LIM domain 5.
   
 
0.575
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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