G3QHV0_GORGO protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

G3QHV0_GORGO

Linker for activation of T cells. (268 aa)

Predicted Functional Partners:

PLCG1

0.996

GRB2

0.988

GRAP2

0.984

G3QGN8_GORGO

0.980

LCP2

0.970

LCK

0.925

SYK

0.897

PLCG2

0.840

VAV1

0.837

GRAP

0.831

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3QGN8_GORGO	G3QHV0_GORGO	ENSGGOP00000001498	ENSGGOP00000001936	Tyrosine-protein kinase.	Linker for activation of T cells.	0.980
G3QGN8_GORGO	GRAP	ENSGGOP00000001498	ENSGGOP00000012426	Tyrosine-protein kinase.	GRB2 related adaptor protein.	0.527
G3QGN8_GORGO	GRAP2	ENSGGOP00000001498	ENSGGOP00000001459	Tyrosine-protein kinase.	GRB2 related adaptor protein 2.	0.875
G3QGN8_GORGO	GRB2	ENSGGOP00000001498	ENSGGOP00000005990	Tyrosine-protein kinase.	Growth factor receptor bound protein 2.	0.909
G3QGN8_GORGO	LCK	ENSGGOP00000001498	ENSGGOP00000032008	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.999
G3QGN8_GORGO	LCP2	ENSGGOP00000001498	ENSGGOP00000006455	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.999
G3QGN8_GORGO	PLCG1	ENSGGOP00000001498	ENSGGOP00000007654	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.896
G3QGN8_GORGO	PLCG2	ENSGGOP00000001498	ENSGGOP00000027884	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.882
G3QGN8_GORGO	SYK	ENSGGOP00000001498	ENSGGOP00000010128	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.723
G3QGN8_GORGO	VAV1	ENSGGOP00000001498	ENSGGOP00000011974	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 1.	0.993
G3QHV0_GORGO	G3QGN8_GORGO	ENSGGOP00000001936	ENSGGOP00000001498	Linker for activation of T cells.	Tyrosine-protein kinase.	0.980
G3QHV0_GORGO	GRAP	ENSGGOP00000001936	ENSGGOP00000012426	Linker for activation of T cells.	GRB2 related adaptor protein.	0.831
G3QHV0_GORGO	GRAP2	ENSGGOP00000001936	ENSGGOP00000001459	Linker for activation of T cells.	GRB2 related adaptor protein 2.	0.984
G3QHV0_GORGO	GRB2	ENSGGOP00000001936	ENSGGOP00000005990	Linker for activation of T cells.	Growth factor receptor bound protein 2.	0.988
G3QHV0_GORGO	LCK	ENSGGOP00000001936	ENSGGOP00000032008	Linker for activation of T cells.	Tyrosine-protein kinase.	0.925
G3QHV0_GORGO	LCP2	ENSGGOP00000001936	ENSGGOP00000006455	Linker for activation of T cells.	Lymphocyte cytosolic protein 2.	0.970
G3QHV0_GORGO	PLCG1	ENSGGOP00000001936	ENSGGOP00000007654	Linker for activation of T cells.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.996
G3QHV0_GORGO	PLCG2	ENSGGOP00000001936	ENSGGOP00000027884	Linker for activation of T cells.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.840
G3QHV0_GORGO	SYK	ENSGGOP00000001936	ENSGGOP00000010128	Linker for activation of T cells.	Tyrosine-protein kinase.	0.897
G3QHV0_GORGO	VAV1	ENSGGOP00000001936	ENSGGOP00000011974	Linker for activation of T cells.	Vav guanine nucleotide exchange factor 1.	0.837