Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (761 aa)    
Predicted Functional Partners:
ACAA1
Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.996
SCP2
Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family.
   
0.993
ACOX1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.988
ACOX2
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.983
ACOX3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.978
CAT
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
   
 0.932
CHAT
Choline O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family.
   
 0.903
CRAT
Carnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family.
   
 0.903
CPT2
Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family.
   
 
 0.879
ENSGGOP00000043765
Peroxisomal biogenesis factor 5.
   
 0.846
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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