Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANKFY1Ankyrin repeat and FYVE domain containing 1. (1127 aa)    
Predicted Functional Partners:
PIK3R4
Phosphoinositide-3-kinase regulatory subunit 4.
     
 0.836
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.823
SNX27
Sorting nexin 27.
    
 0.819
G3QDM5_GORGO
EH domain containing 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 
 0.800
VPS26A
Uncharacterized protein.
    
 0.791
RAB5A
RAB5A, member RAS oncogene family.
   
 0.736
RAB7A
RAB7A, member RAS oncogene family.
    
 0.720
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
    
 0.716
TBC1D8B
TBC1 domain family member 8B.
   
 
 0.705
VPS26B
VPS26, retromer complex component B.
    
 0.694
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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