| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DPYSL2 | G3RTG9_GORGO | ENSGGOP00000030619 | ENSGGOP00000019094 | Dihydropyrimidinase like 2. | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | 0.503 |
| DPYSL2 | NUMB | ENSGGOP00000030619 | ENSGGOP00000032937 | Dihydropyrimidinase like 2. | NUMB endocytic adaptor protein. | 0.824 |
| DPYSL2 | NUMBL | ENSGGOP00000030619 | ENSGGOP00000019253 | Dihydropyrimidinase like 2. | NUMB like endocytic adaptor protein. | 0.608 |
| EPS15 | G3RTG9_GORGO | ENSGGOP00000025507 | ENSGGOP00000019094 | Epidermal growth factor receptor pathway substrate 15. | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | 0.990 |
| EPS15 | NUMB | ENSGGOP00000025507 | ENSGGOP00000032937 | Epidermal growth factor receptor pathway substrate 15. | NUMB endocytic adaptor protein. | 0.840 |
| EPS15 | NUMBL | ENSGGOP00000025507 | ENSGGOP00000019253 | Epidermal growth factor receptor pathway substrate 15. | NUMB like endocytic adaptor protein. | 0.785 |
| G3RTG9_GORGO | DPYSL2 | ENSGGOP00000019094 | ENSGGOP00000030619 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | Dihydropyrimidinase like 2. | 0.503 |
| G3RTG9_GORGO | EPS15 | ENSGGOP00000019094 | ENSGGOP00000025507 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | Epidermal growth factor receptor pathway substrate 15. | 0.990 |
| G3RTG9_GORGO | NUMB | ENSGGOP00000019094 | ENSGGOP00000032937 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | NUMB endocytic adaptor protein. | 0.862 |
| G3RTG9_GORGO | NUMBL | ENSGGOP00000019094 | ENSGGOP00000019253 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | NUMB like endocytic adaptor protein. | 0.850 |
| ITCH | NOTCH1 | ENSGGOP00000007084 | ENSGGOP00000009720 | E3 ubiquitin-protein ligase. | Uncharacterized protein. | 0.977 |
| ITCH | NOTCH2 | ENSGGOP00000007084 | ENSGGOP00000003937 | E3 ubiquitin-protein ligase. | Notch receptor 2. | 0.938 |
| ITCH | NOTCH3 | ENSGGOP00000007084 | ENSGGOP00000002228 | E3 ubiquitin-protein ligase. | Notch receptor 3. | 0.939 |
| ITCH | NOTCH4 | ENSGGOP00000007084 | ENSGGOP00000002300 | E3 ubiquitin-protein ligase. | Notch receptor 4. | 0.935 |
| ITCH | NUMB | ENSGGOP00000007084 | ENSGGOP00000032937 | E3 ubiquitin-protein ligase. | NUMB endocytic adaptor protein. | 0.954 |
| ITCH | NUMBL | ENSGGOP00000007084 | ENSGGOP00000019253 | E3 ubiquitin-protein ligase. | NUMB like endocytic adaptor protein. | 0.924 |
| LNX1 | NUMB | ENSGGOP00000009814 | ENSGGOP00000032937 | Ligand of numb-protein X 1. | NUMB endocytic adaptor protein. | 0.918 |
| LNX1 | NUMBL | ENSGGOP00000009814 | ENSGGOP00000019253 | Ligand of numb-protein X 1. | NUMB like endocytic adaptor protein. | 0.853 |
| NOTCH1 | ITCH | ENSGGOP00000009720 | ENSGGOP00000007084 | Uncharacterized protein. | E3 ubiquitin-protein ligase. | 0.977 |
| NOTCH1 | NOTCH2 | ENSGGOP00000009720 | ENSGGOP00000003937 | Uncharacterized protein. | Notch receptor 2. | 0.986 |
