ELOC protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ELOC

Elongin C; Belongs to the SKP1 family. (112 aa)

Predicted Functional Partners:

ELOB

0.999

CUL5

0.999

HIF1A

0.994

VHL

0.993

CUL2

0.993

EPAS1

0.985

RNF7

0.974

ENSGGOP00000045589

0.971

SOCS2

0.959

APOBEC3G

0.951

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOBEC3G	CUL5	ENSGGOP00000021965	ENSGGOP00000027637	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Cullin 5; Belongs to the cullin family.	0.976
APOBEC3G	ELOB	ENSGGOP00000021965	ENSGGOP00000014931	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Elongin B.	0.964
APOBEC3G	ELOC	ENSGGOP00000021965	ENSGGOP00000002153	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Elongin C; Belongs to the SKP1 family.	0.951
APOBEC3G	ENSGGOP00000045589	ENSGGOP00000021965	ENSGGOP00000045589	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Ubiquitin-like domain-containing protein.	0.502
APOBEC3G	RNF7	ENSGGOP00000021965	ENSGGOP00000001803	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	Ring finger protein 7.	0.947
CUL2	CUL5	ENSGGOP00000039738	ENSGGOP00000027637	Cullin 2; Belongs to the cullin family.	Cullin 5; Belongs to the cullin family.	0.865
CUL2	ELOB	ENSGGOP00000039738	ENSGGOP00000014931	Cullin 2; Belongs to the cullin family.	Elongin B.	0.998
CUL2	ELOC	ENSGGOP00000039738	ENSGGOP00000002153	Cullin 2; Belongs to the cullin family.	Elongin C; Belongs to the SKP1 family.	0.993
CUL2	ENSGGOP00000045589	ENSGGOP00000039738	ENSGGOP00000045589	Cullin 2; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.979
CUL2	EPAS1	ENSGGOP00000039738	ENSGGOP00000034122	Cullin 2; Belongs to the cullin family.	Uncharacterized protein.	0.977
CUL2	HIF1A	ENSGGOP00000039738	ENSGGOP00000028093	Cullin 2; Belongs to the cullin family.	Hypoxia inducible factor 1 subunit alpha.	0.996
CUL2	RNF7	ENSGGOP00000039738	ENSGGOP00000001803	Cullin 2; Belongs to the cullin family.	Ring finger protein 7.	0.989
CUL2	SOCS2	ENSGGOP00000039738	ENSGGOP00000009942	Cullin 2; Belongs to the cullin family.	Suppressor of cytokine signaling 2.	0.455
CUL2	VHL	ENSGGOP00000039738	ENSGGOP00000010193	Cullin 2; Belongs to the cullin family.	Von Hippel-Lindau tumor suppressor.	0.999
CUL5	APOBEC3G	ENSGGOP00000027637	ENSGGOP00000021965	Cullin 5; Belongs to the cullin family.	DNA dC->dU-editing enzyme APOBEC-3G; DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the p [...]	0.976
CUL5	CUL2	ENSGGOP00000027637	ENSGGOP00000039738	Cullin 5; Belongs to the cullin family.	Cullin 2; Belongs to the cullin family.	0.865
CUL5	ELOB	ENSGGOP00000027637	ENSGGOP00000014931	Cullin 5; Belongs to the cullin family.	Elongin B.	0.999
CUL5	ELOC	ENSGGOP00000027637	ENSGGOP00000002153	Cullin 5; Belongs to the cullin family.	Elongin C; Belongs to the SKP1 family.	0.999
CUL5	ENSGGOP00000045589	ENSGGOP00000027637	ENSGGOP00000045589	Cullin 5; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.978
CUL5	RNF7	ENSGGOP00000027637	ENSGGOP00000001803	Cullin 5; Belongs to the cullin family.	Ring finger protein 7.	0.999